Isoform-Specific Modulation of Inflammation Induced by Adenoviral Mediated Delivery of Platelet-Derived Growth Factors in the Adult Mouse Heart

Platelet-derived growth factors (PDGFs) are key regulators of mesenchymal cells in vertebrate development. To what extent PDGFs also exert beneficial homeostatic or reparative roles in adult organs, as opposed to adverse fibrogenic responses in pathology, are unclear. PDGF signaling plays critical r...

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Udgivet i:PLoS One
Main Authors: Gallini, Radiosa, Huusko, Jenni, Ylä-Herttuala, Seppo, Betsholtz, Christer, Andrae, Johanna
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4981378/
https://ncbi.nlm.nih.gov/pubmed/27513343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160930
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