AMPK Mediates Glucocorticoids Stress-Induced Downregulation of the Glucocorticoid Receptor in Cultured Rat Prefrontal Cortical Astrocytes

Chronic stress induces altered energy metabolism and plays important roles in the etiology of depression, in which the glucocorticoid negative feedback is disrupted due to imbalanced glucocorticoid receptor (GR) functions. The mechanism underlying the dysregulation of GR by chronic stress remains el...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Yuan, Shi-Ying, Liu, Jue, Zhou, Jun, Lu, Wei, Zhou, Hai-Yun, Long, Li-Hong, Hu, Zhuang-Li, Ni, Lan, Wang, Yi, Chen, Jian-Guo, Wang, Fang
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2016
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4981361/
https://ncbi.nlm.nih.gov/pubmed/27513844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159513
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