Inactivation of SmeSyRy Two-Component Regulatory System Inversely Regulates the Expression of SmeYZ and SmeDEF Efflux Pumps in Stenotrophomonas maltophilia

SmeYZ efflux pump is a critical pump responsible for aminoglycosides resistance, virulence-related characteristics (oxidative stress susceptibility, motility, and secreted protease activity), and virulence in Stenotrophomonas maltophilia. However, the regulatory circuit involved in SmeYZ expression...

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Veröffentlicht in:PLoS One
Hauptverfasser: Wu, Chao-Jung, Huang, Yi-Wei, Lin, Yi-Tsung, Ning, Hsiao-Chen, Yang, Tsuey-Ching
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4981351/
https://ncbi.nlm.nih.gov/pubmed/27513575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160943
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