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Hedgehog pathway inhibition in advanced basal cell carcinoma: latest evidence and clinical usefulness

Treatment of locally advanced basal cell carcinomas (laBCCs) with large, aggressive, destructive, and disfiguring tumors, or metastatic disease is challenging. Dysregulation of the Hedgehog (Hh) signaling pathway has been identified in the vast majority of basal cell carcinomas (BCCs). There are two...

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Bibliographische Detailangaben
Veröffentlicht in:Ther Adv Med Oncol
Hauptverfasser: Silapunt, Sirunya, Chen, Leon, Migden, Michael R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: SAGE Publications 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4981290/
https://ncbi.nlm.nih.gov/pubmed/27583029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1758834016653605
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