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Solubility as a limiting factor for expression of hepatitis A virus proteins in insect cell-baculovirus system

The use of recombinant proteins may represent an alternative model to inactivated vaccines against hepatitis A virus (HAV). The present study aimed to express the VP1 protein of HAV in baculovirus expression vector system (BEVS). The VP1 was expressed intracellularly with molecular mass of 35 kDa. T...

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Bibliografische gegevens
Gepubliceerd in:Mem Inst Oswaldo Cruz
Hoofdauteurs: da Silva, Haroldo Cid, Pestana, Cristiane Pinheiro, Galler, Ricardo, Medeiros, Marco Alberto
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Instituto Oswaldo Cruz, Ministério da Saúde 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4981117/
https://ncbi.nlm.nih.gov/pubmed/27581123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/0074-02760160153
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