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Role of fosaprepitant, a neurokinin Type 1 receptor antagonist, in morphine-induced antinociception in rats

OBJECTIVES: Opioids such as morphine form the cornerstone in the treatment of moderate to severe pain. However, opioids also produce serious side effects such as tolerance. Fosaprepitant is a substance P (SP) receptor antagonist, which is used for treating chemotherapy-induced nausea and vomiting. S...

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Detalhes bibliográficos
Publicado no:Indian J Pharmacol
Main Authors: Prasoon, Pranav, Gupta, Shivani, Kumar, Rahul, Gautam, Mayank, Kaler, Saroj, Ray, Subrata Basu
Formato: Artigo
Idioma:Inglês
Publicado em: Medknow Publications & Media Pvt Ltd 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4980927/
https://ncbi.nlm.nih.gov/pubmed/27756950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0253-7613.186198
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