Nephroprotective effects of enalapril after [177Lu]-DOTATATE therapy using serial renal scintigraphies in a murine model of radiation-induced nephropathy

BACKGROUND: Radiation-induced nephropathy is still dose limiting in radionuclide therapy of neuroendocrine tumors. We investigated the nephroprotective potential of the angiotensine converting enzyme inhibiting drug enalpril after [177Lu]-DOTATATE therapy in a murine model of radiation-induced nephr...

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Detalhes bibliográficos
Publicado no:EJNMMI Res
Main Authors: Ilhan, Harun, Wang, Hao, Gildehaus, Franz J., Wängler, Carmen, Herrler, Tanja, Todica, Andrei, Schlichtiger, Julia, Cumming, Paul, Bartenstein, Peter, Hacker, Marcus, Haug, Alexander R.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2016
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4980865/
https://ncbi.nlm.nih.gov/pubmed/27515447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-016-0219-2
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