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A virtual lymph node model to dissect the requirements for T-cell activation by synapses and kinapses

The initiation of T-cell responses in lymph nodes requires T cells to integrate signals delivered by dendritic cells (DCs) during long-lasting contacts (synapses) or more transient interactions (kinapses). However, it remains extremely challenging to understand how a specific sequence of contacts es...

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Bibliographische Detailangaben
Veröffentlicht in:Immunol Cell Biol
Hauptverfasser: Moreau, Hélène D, Bogle, Gib, Bousso, Philippe
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4980574/
https://ncbi.nlm.nih.gov/pubmed/27089942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2016.36
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