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Effect of Renal Dysfunction on Toxicity in Three Decades of Cancer Therapy Evaluation Program–Sponsored Single-Agent Phase I Studies

PURPOSE: Alterations in renal clearance of anticancer drugs can affect the occurrence of toxicities related to drug exposure. The National Cancer Institute and the US Food and Drug Administration (FDA) use different criteria to classify renal dysfunction. We examined those discrepancies and their po...

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Detalhes bibliográficos
Publicado no:J Clin Oncol
Main Authors: Beumer, Jan H., Ding, Fei, Tawbi, Hussein, Lin, Yan, Viluh, Diana, Chatterjee, Indrani, Rinker, Matthew, Chow, Selina L., Ivy, S. Percy
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4980565/
https://ncbi.nlm.nih.gov/pubmed/26392101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2014.59.7302
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