Comparison of FDA Approved Kinase Targets to Clinical Trial Ones: Insights from Their System Profiles and Drug-Target Interaction Networks

Kinase is one of the most productive classes of established targets, but the majority of approved drugs against kinase were developed only for cancer. Intensive efforts were therefore exerted for releasing its therapeutic potential by discovering new therapeutic area. Kinases in clinical trial could...

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Detalhes bibliográficos
Publicado no:Biomed Res Int
Main Authors: Xu, Jingyu, Wang, Panpan, Yang, Hong, Zhou, Jin, Li, Yinghong, Li, Xiaoxu, Xue, Weiwei, Yu, Chunyan, Tian, Yubin, Zhu, Feng
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4980536/
https://ncbi.nlm.nih.gov/pubmed/27547755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/2509385
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