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Structure of a Complete ATP Synthase Dimer Reveals the Molecular Basis of Inner Mitochondrial Membrane Morphology

We determined the structure of a complete, dimeric F(1)F(o)-ATP synthase from yeast Yarrowia lipolytica mitochondria by a combination of cryo-EM and X-ray crystallography. The final structure resolves 58 of the 60 dimer subunits. Horizontal helices of subunit a in F(o) wrap around the c-ring rotor,...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Hahn, Alexander, Parey, Kristian, Bublitz, Maike, Mills, Deryck J., Zickermann, Volker, Vonck, Janet, Kühlbrandt, Werner, Meier, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4980432/
https://ncbi.nlm.nih.gov/pubmed/27373333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.05.037
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