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Ctf4 Links DNA Replication with Sister Chromatid Cohesion Establishment by Recruiting the Chl1 Helicase to the Replisome

DNA replication during S phase is accompanied by establishment of sister chromatid cohesion to ensure faithful chromosome segregation. The Eco1 acetyltransferase, helped by factors including Ctf4 and Chl1, concomitantly acetylates the chromosomal cohesin complex to stabilize its cohesive links. Here...

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Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Samora, Catarina P., Saksouk, Julie, Goswami, Panchali, Wade, Ben O., Singleton, Martin R., Bates, Paul A., Lengronne, Armelle, Costa, Alessandro, Uhlmann, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4980427/
https://ncbi.nlm.nih.gov/pubmed/27397686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.05.036
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