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Ctf4 Links DNA Replication with Sister Chromatid Cohesion Establishment by Recruiting the Chl1 Helicase to the Replisome

DNA replication during S phase is accompanied by establishment of sister chromatid cohesion to ensure faithful chromosome segregation. The Eco1 acetyltransferase, helped by factors including Ctf4 and Chl1, concomitantly acetylates the chromosomal cohesin complex to stabilize its cohesive links. Here...

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Publicado en:Mol Cell
Autores principales: Samora, Catarina P., Saksouk, Julie, Goswami, Panchali, Wade, Ben O., Singleton, Martin R., Bates, Paul A., Lengronne, Armelle, Costa, Alessandro, Uhlmann, Frank
Formato: Artigo
Lenguaje:Inglês
Publicado: Cell Press 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4980427/
https://ncbi.nlm.nih.gov/pubmed/27397686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.05.036
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