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The genetic epidemiology of the form of microcephaly ascribed to mutation at the WDR62 locus

The disorder associated with mutation in the WDR62 gene MCPH2 is taken as the prototype of a condition which has a recessive mode of inheritance. The mutant homozygote has relatively lower fitness defined by the selection coefficient. Formulae which relate the incidence of the disorder to the mutati...

詳細記述

保存先:
書誌詳細
出版年:Ann Transl Med
第一著者: Stark, Alan Edmund
フォーマット: Artigo
言語:Inglês
出版事項: AME Publishing Company 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4980368/
https://ncbi.nlm.nih.gov/pubmed/27570775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm.2016.07.08
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