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The genetic epidemiology of the form of microcephaly ascribed to mutation at the WDR62 locus

The disorder associated with mutation in the WDR62 gene MCPH2 is taken as the prototype of a condition which has a recessive mode of inheritance. The mutant homozygote has relatively lower fitness defined by the selection coefficient. Formulae which relate the incidence of the disorder to the mutati...

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Bibliografske podrobnosti
izdano v:Ann Transl Med
Glavni avtor: Stark, Alan Edmund
Format: Artigo
Jezik:Inglês
Izdano: AME Publishing Company 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4980368/
https://ncbi.nlm.nih.gov/pubmed/27570775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm.2016.07.08
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