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The genetic epidemiology of the form of microcephaly ascribed to mutation at the WDR62 locus
The disorder associated with mutation in the WDR62 gene MCPH2 is taken as the prototype of a condition which has a recessive mode of inheritance. The mutant homozygote has relatively lower fitness defined by the selection coefficient. Formulae which relate the incidence of the disorder to the mutati...
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| Pubblicato in: | Ann Transl Med |
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| Autore principale: | |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
AME Publishing Company
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4980368/ https://ncbi.nlm.nih.gov/pubmed/27570775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/atm.2016.07.08 |
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