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Inhibition of human norovirus by a viral polymerase inhibitor in the B cell culture system and in the mouse model

The recently developed human norovirus (HuNoV) B cell culture and mouse models hold promise for drug discovery and development but their suitability for antiviral studies has not been assessed. We demonstrate the inhibitory effect of the nucleoside analogue 2′-C-methylcytidine (2CMC) on HuNoV replic...

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Dettagli Bibliografici
Pubblicato in:Antiviral Res
Autori principali: Kolawole, Abimbola O., Rocha-Pereira, Joana, Elftman, Michael D., Neyts, Johan, Wobus, Christiane E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4980194/
https://ncbi.nlm.nih.gov/pubmed/27210811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2016.05.011
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