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Inhibition of human norovirus by a viral polymerase inhibitor in the B cell culture system and in the mouse model

The recently developed human norovirus (HuNoV) B cell culture and mouse models hold promise for drug discovery and development but their suitability for antiviral studies has not been assessed. We demonstrate the inhibitory effect of the nucleoside analogue 2′-C-methylcytidine (2CMC) on HuNoV replic...

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Detalhes bibliográficos
Publicado no:Antiviral Res
Main Authors: Kolawole, Abimbola O., Rocha-Pereira, Joana, Elftman, Michael D., Neyts, Johan, Wobus, Christiane E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4980194/
https://ncbi.nlm.nih.gov/pubmed/27210811
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2016.05.011
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