Adenosine-Induced Atrial Fibrillation: Localized Reentrant Drivers in Lateral Right Atria due to Heterogeneous Expression of Adenosine A1 Receptors and GIRK4 Subunits in the Human Heart

BACKGROUND: Adenosine provokes atrial fibrillation (AF) with a higher activation frequency in right atria (RA) versus left atria (LA) in patients, but the underlying molecular and functional substrates are unclear. We tested the hypothesis that adenosine-induced AF is driven by localized reentry in...

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Publicado no:Circulation
Main Authors: Li, Ning, Csepe, Thomas A., Hansen, Brian J., Sul, Lidiya V., Kalyanasundaram, Anuradha, Zakharkin, Stanislav O., Zhao, Jichao, Guha, Avirup, Van Wagoner, David R., Kilic, Ahmet, Mohler, Peter J, Janssen, Paul ML, Biesiadecki, Brandon, Hummel, John D, Weiss, Raul, Fedorov, Vadim V.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4980184/
https://ncbi.nlm.nih.gov/pubmed/27462069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.115.021165
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