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Single cell analysis demonstrates how nutrient deprivation creates apoptotic and quiescent cell populations in tumor cylindroids

Understanding how quiescent and apoptotic populations form in tumors is necessary because these cell types can considerably diminish therapeutic efficacy. Most cancer therapeutics are ineffective against quiescent cells because they target rapidly proliferating cells. Distinguishing apoptosis is imp...

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Detalhes bibliográficos
Publicado no:Biotechnol Bioeng
Main Authors: Kim, Byoung-jin, Forbes, Neil S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4979974/
https://ncbi.nlm.nih.gov/pubmed/18814293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.21985
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