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Discovery of an inhibitor of the production of the Pseudomonas aeruginosa virulence factor pyocyanin in wild-type cells

Pyocyanin is a small molecule produced by Pseudomonas aeruginosa that plays a crucial role in the pathogenesis of infections by this notorious opportunistic pathogen. The inhibition of pyocyanin production has been identified as an attractive antivirulence strategy for the treatment of P. aeruginosa...

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Publicat a:Beilstein J Org Chem
Autors principals: Morkunas, Bernardas, Gal, Balint, Galloway, Warren R J D, Hodgkinson, James T, Ibbeson, Brett M, Sing Tan, Yaw, Welch, Martin, Spring, David R
Format: Artigo
Idioma:Inglês
Publicat: Beilstein-Institut 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4979876/
https://ncbi.nlm.nih.gov/pubmed/27559393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.12.137
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