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Discovery of an inhibitor of the production of the Pseudomonas aeruginosa virulence factor pyocyanin in wild-type cells

Pyocyanin is a small molecule produced by Pseudomonas aeruginosa that plays a crucial role in the pathogenesis of infections by this notorious opportunistic pathogen. The inhibition of pyocyanin production has been identified as an attractive antivirulence strategy for the treatment of P. aeruginosa...

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Detalhes bibliográficos
Publicado no:Beilstein J Org Chem
Main Authors: Morkunas, Bernardas, Gal, Balint, Galloway, Warren R J D, Hodgkinson, James T, Ibbeson, Brett M, Sing Tan, Yaw, Welch, Martin, Spring, David R
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4979876/
https://ncbi.nlm.nih.gov/pubmed/27559393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.12.137
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