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Role of rap1B and p21ras GTPase-activating protein in the regulation of phospholipase C-gamma 1 in human platelets.

Thrombin activates phospholipase C in human platelets, but the specific isoenzymes activated and the signal pathway used are unknown. Using specific antibodies, we found that phospholipase C-gamma 1 and the p21ras GTPase-activating protein, rasGAP, are present in human platelets. Furthermore, phosph...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Torti, M, Lapetina, E G
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1992
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49798/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1323853/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.16.7796
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