Nociceptive Sensitizers Are Regulated in Damaged Joint Tissues, Including Articular Cartilage, When Osteoarthritic Mice Display Pain Behavior

OBJECTIVE: Pain is the most common symptom of osteoarthritis (OA), yet where it originates in the joint and how it is driven are unknown. The aim of this study was to identify pain‐sensitizing molecules that are regulated in the joint when mice subjected to surgical joint destabilization develop OA‐...

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Bibliographic Details
Published in:Arthritis Rheumatol
Main Authors: Driscoll, Clare, Chanalaris, Anastasios, Knights, Chancie, Ismail, Heba, Sacitharan, Pradeep K., Gentry, Clive, Bevan, Stuart, Vincent, Tonia L.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2016
Subjects:
Osteoarthritis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4979655/
https://ncbi.nlm.nih.gov/pubmed/26605536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39523
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