Dual epithelial and immune cell function of Dvl1 regulates gut microbiota composition and intestinal homeostasis

Homeostasis of the gastrointestinal (GI) tract is controlled by complex interactions between epithelial and immune cells and the resident microbiota. Here, we studied the role of Wnt signaling in GI homeostasis using Disheveled 1 knockout (Dvl1(–/–)) mice, which display an increase in whole gut tran...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Belinson, Haim, Savage, Adam K., Fadrosh, Douglas, Kuo, Yien-Ming, Lin, Din, Valladares, Ricardo, Nusse, Ysbrand, Wynshaw-Boris, Anthony, Lynch, Susan V., Locksley, Richard M., Klein, Ophir D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4979554/
https://ncbi.nlm.nih.gov/pubmed/27525310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.85395
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