Disclosing Pleiotropic Effects during Genetic Risk Assessment for Alzheimer’s Disease: A Randomized, Controlled Trial

BACKGROUND: Increasing use of genetic testing raises questions about disclosing secondary findings, including pleiotropic information. OBJECTIVE: To determine the safety and behavioral impact of disclosing modest associations between APOE genotype and coronary artery disease (CAD) risk during APOE-b...

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Foilsithe in:Ann Intern Med
Main Authors: Christensen, Kurt D., Roberts, J. Scott, Whitehouse, Peter J., Royal, Charmaine D. M., Obisesan, Thomas O., Cupples, L. Adrienne, Vernarelli, Jacqueline A., Bhatt, Deepak L., Linnenbringer, Erin, Butson, Melissa B., Fasaye, Grace-Ann, Uhlmann, Wendy R., Hiraki, Susan, Wang, Na, Cook-Deegan, Robert, Green, Robert C.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2016
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4979546/
https://ncbi.nlm.nih.gov/pubmed/26810768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7326/M15-0187
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