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Cytotoxic L-amino-acid oxidases from Amanita phalloides and Clitocybe geotropa induce caspase-dependent apoptosis

L-amino-acid oxidases (LAO) purified from fungi induce cell death in various mammalian cells including human tumor cell lines. The mechanism, however, remains poorly understood. In this study, we aimed to define a precise mechanism of cell death induced in Jurkat and MCF7 cancer cell lines by ApLAO...

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Bibliografske podrobnosti
izdano v:Cell Death Discov
Main Authors: Pišlar, A, Sabotič, J, Šlenc, J, Brzin, J, Kos, J
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4979486/
https://ncbi.nlm.nih.gov/pubmed/27551514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddiscovery.2016.21
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