Helicobacter pylori VacA induces apoptosis by accumulation of connexin 43 in autophagic vesicles via a Rac1/ERK-dependent pathway

Helicobacter pylori (H. pylori) produces vacuolating cytotoxin (VacA), a potent protein toxin, which is associated with gastric inflammation and ulceration. Recent studies demonstrated that connexins (Cxs), which are responsible for intracellular communication at gap junctions (GJs) as well as cell...

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Detalhes bibliográficos
Publicado no:Cell Death Discov
Main Authors: Yahiro, K, Akazawa, Y, Nakano, M, Suzuki, H, Hisatune, J, Isomoto, H, Sap, J, Noda, M, Moss, J, Hirayama, T
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4979424/
https://ncbi.nlm.nih.gov/pubmed/27551466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddiscovery.2015.35
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