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The transposable element environment of human genes is associated with histone and expression changes in cancer

BACKGROUND: Only 2 % of the human genome code for proteins. Among the remaining 98 %, transposable elements (TEs) represent millions of sequences. TEs have an impact on genome evolution by promoting mutations. Especially, TEs possess their own regulatory sequences and can alter the expression patter...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Grégoire, Laura, Haudry, Annabelle, Lerat, Emmanuelle
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4979156/
https://ncbi.nlm.nih.gov/pubmed/27506777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-016-2970-1
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