Polycythemia Vera: An Appraisal of the Biology and Management 10 Years After the Discovery of JAK2 V617F

Polycythemia vera (PV) is a chronic myeloproliferative neoplasm that is associated with a substantial symptom burden, thrombohemorrhagic complications, and impaired survival. A decade after the seminal discovery of an activating mutation in the tyrosine kinase JAK2 in nearly all patients with PV, ne...

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Detalhes bibliográficos
Publicado no:J Clin Oncol
Main Authors: Stein, Brady L., Oh, Stephen T., Berenzon, Dmitriy, Hobbs, Gabriela S., Kremyanskaya, Marina, Rampal, Raajit K., Abboud, Camille N., Adler, Kenneth, Heaney, Mark L., Jabbour, Elias J., Komrokji, Rami S., Moliterno, Alison R., Ritchie, Ellen K., Rice, Lawrence, Mascarenhas, John, Hoffman, Ronald
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Clinical Oncology 2015
Assuntos:
Review Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4979103/
https://ncbi.nlm.nih.gov/pubmed/26324368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2015.61.6474
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