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Sodium MRI in Multiple Sclerosis is Compatible with Intracellular Sodium Accumulation and Inflammation-Induced Hyper-Cellularity of Acute Brain Lesions

The cascade of inflammatory pathogenetic mechanisms in multiple sclerosis (MS) has no specific conventional MRI correlates. Clinicians therefore stipulate improved imaging specificity to define the pathological substrates of MS in vivo including mapping of intracellular sodium accumulation. Based up...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Biller, Armin, Pflugmann, Isabella, Badde, Stephanie, Diem, Ricarda, Wildemann, Brigitte, Nagel, Armin M., Jordan, J., Benkhedah, Nadia, Kleesiek, Jens
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4978993/
https://ncbi.nlm.nih.gov/pubmed/27507776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31269
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