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A Chromatin-Focused siRNA Screen for Regulators of p53-Dependent Transcription

The protein product of the Homo sapiens TP53 gene is a transcription factor (p53) that regulates the expression of genes critical for the response to DNA damage and tumor suppression, including genes involved in cell cycle arrest, apoptosis, DNA repair, metabolism, and a number of other tumorigenesi...

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Pubblicato in:G3 (Bethesda)
Autori principali: Sammons, Morgan A., Zhu, Jiajun, Berger, Shelley L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Genetics Society of America 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4978920/
https://ncbi.nlm.nih.gov/pubmed/27334938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.116.031534
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