miR-155 Deletion in Mice Overcomes Neuron-Intrinsic and Neuron-Extrinsic Barriers to Spinal Cord Repair

Axon regeneration after spinal cord injury (SCI) fails due to neuron-intrinsic mechanisms and extracellular barriers including inflammation. microRNA (miR)-155–5p is a small, noncoding RNA that negatively regulates mRNA translation. In macrophages, miR-155-5p is induced by inflammatory stimuli and e...

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Publicado no:J Neurosci
Main Authors: Gaudet, Andrew D., Mandrekar-Colucci, Shweta, Hall, Jodie C.E., Sweet, David R., Schmitt, Philipp J., Xu, Xinyang, Guan, Zhen, Mo, Xiaokui, Guerau-de-Arellano, Mireia, Popovich, Phillip G.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2016
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4978808/
https://ncbi.nlm.nih.gov/pubmed/27511021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0735-16.2016
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