Compartment-Dependent Degradation of Mutant Huntingtin Accounts for Its Preferential Accumulation in Neuronal Processes

Lignende værker

• Preferential accumulation of N-terminal mutant huntingtin in the nuclei of striatal neurons is regulated by phosphorylation
  af: Havel, Lauren S., et al.
  Udgivet: (2011)
• Inhibiting the ubiquitin–proteasome system leads to preferential accumulation of toxic N-terminal mutant huntingtin fragments
  af: Li, Xiang, et al.
  Udgivet: (2010)
• Differential Activities of the Ubiquitin–Proteasome System in Neurons versus Glia May Account for the Preferential Accumulation of Misfolded Proteins in Neurons
  af: Tydlacka, Suzanne, et al.
  Udgivet: (2008)
• Clearance of mutant huntingtin
  af: Li, Xiao-Jiang, et al.
  Udgivet: (2010)
• Lack of interleukin-1 type 1 receptor enhances the accumulation of mutant huntingtin in the striatum and exacerbates the neurological phenotypes of Huntington's disease mice
  af: Wang, Chuan-En, et al.
  Udgivet: (2010)