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Brain-derived neurotrophic factor differentially modulates excitability of two classes of hippocampal output neurons

Brain-derived neurotrophic factor (BDNF) plays an important role in hippocampus-dependent learning and memory. Canonically, this has been ascribed to an enhancing effect on neuronal excitability and synaptic plasticity in the CA1 region. However, it is the pyramidal neurons in the subiculum that for...

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Detalhes bibliográficos
Publicado no:J Neurophysiol
Main Authors: Graves, A. R., Moore, S. J., Spruston, N., Tryba, A. K., Kaczorowski, C. C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4978785/
https://ncbi.nlm.nih.gov/pubmed/27146982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00186.2016
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