Spironolactone Prevents Endothelial Nitric Oxide Synthase Uncoupling and Vascular Dysfunction Induced by β-Adrenergic Overstimulation: Role of Perivascular Adipose Tissue

Sustained stimulation of β-adrenoceptors (β-ARs) and activation of renin–angiotensin–aldosterone system are common features of cardiovascular diseases with rising sympathetic activation, including essential hypertension, myocardial infarction, and heart failure. In this study, we investigated the ro...

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Bibliographic Details
Published in:Hypertension
Main Authors: Victorio, Jamaira A., Clerici, Stefano P., Palacios, Roberto, Alonso, María J., Vassallo, Dalton V., Jaffe, Iris Z., Rossoni, Luciana V., Davel, Ana P.
Format: Artigo
Language:Inglês
Published: Lippincott, Williams & Wilkins 2016
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4978608/
https://ncbi.nlm.nih.gov/pubmed/27432866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.116.07911
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