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Genetic Barrier to Direct Acting Antivirals in HCV Sequences Deposited in the European Databank

BACKGROUND & AIMS: Development of resistance results from mutations in the viral genome, and the presence of selective drug pressure leads to the emergence of a resistant virus population. The aim of this study was to analyze the impact of genetic variability on the genetic barrier to drug resis...

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Publicado en:PLoS One
Autores principales: Kliemann, Dimas Alexandre, Tovo, Cristiane Valle, Gorini da Veiga, Ana Beatriz, Machado, André Luiz, West, John
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4978475/
https://ncbi.nlm.nih.gov/pubmed/27504952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159924
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