Natural Cubic Spline Regression Modeling Followed by Dynamic Network Reconstruction for the Identification of Radiation-Sensitivity Gene Association Networks from Time-Course Transcriptome Data

Gene expression time-course experiments allow to study the dynamics of transcriptomic changes in cells exposed to different stimuli. However, most approaches for the reconstruction of gene association networks (GANs) do not propose prior-selection approaches tailored to time-course transcriptome dat...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Michna, Agata, Braselmann, Herbert, Selmansberger, Martin, Dietz, Anne, Hess, Julia, Gomolka, Maria, Hornhardt, Sabine, Blüthgen, Nils, Zitzelsberger, Horst, Unger, Kristian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4978405/
https://ncbi.nlm.nih.gov/pubmed/27505168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160791
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