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ModA2 Phasevarion Switching in Nontypeable Haemophilus influenzae Increases the Severity of Experimental Otitis Media

Several human-adapted bacterial pathogens use a phasevarion (ie, a phase-variable regulon) to rapidly and reversibly regulate the expression of many genes, which include known virulence factors, yet the influence of phasevarion-mediated regulation in pathogenesis remains poorly understood. Here we e...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Brockman, Kenneth L., Jurcisek, Joseph A., Atack, John M., Srikhanta, Yogitha N., Jennings, Michael P., Bakaletz, Lauren O.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4978376/
https://ncbi.nlm.nih.gov/pubmed/27288538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw243
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