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Viral binding-induced signaling drives a unique and extended intracellular trafficking pattern during infection of primary monocytes

We initiated experiments to examine the infection of monocytes postentry. New data show that human cytomegalovirus (HCMV) DNA is detected in the nucleus beginning only at 3 d postinfection in monocytes, compared with 30 min postinfection in fibroblasts and endothelial cells, suggesting that HCMV nuc...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Kim, Jung Heon, Collins-McMillen, Donna, Caposio, Patrizia, Yurochko, Andrew D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4978277/
https://ncbi.nlm.nih.gov/pubmed/27432979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1604317113
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