Interaction of Human Brain Acetylcholinesterase with Cyclophosphamide: A Molecular Modeling and Docking Study

This study describes the interaction between human acetylcholinesterase (AChE), a key regulator of central and peripheral cholinergic function, and the widely used nitrogen mustard alkylating agent, cyclophosphamide (CP). Modeling of the AChE sequence (NCBI Accession No: AAI05061.1) was performed us...

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Bibliografiske detaljer
Udgivet i:CNS Neurol Disord Drug Targets
Main Authors: Shakil, Shazi, Khan, Rosina, Tabrez, Shams, Alam, Qamre, Jabir, Nasimudeen R., Sulaiman, Mansour I., Greig, Nigel H., Kamal, Mohammad A.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4978224/
https://ncbi.nlm.nih.gov/pubmed/21999734
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