Fragile X mental retardation protein knockdown in the developing Xenopus tadpole optic tectum results in enhanced feedforward inhibition and behavioral deficits

BACKGROUND: Fragile X Syndrome is the leading monogenetic cause of autism and most common form of intellectual disability. Previous studies have implicated changes in dendritic spine architecture as the primary result of loss of Fragile X Mental Retardation Protein (FMRP), but recent work has shown...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Neural Dev
Auteurs principaux: Truszkowski, Torrey L. S., James, Eric J., Hasan, Mashfiq, Wishard, Tyler J., Liu, Zhenyu, Pratt, Kara G., Cline, Hollis T., Aizenman, Carlos D.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4977860/
https://ncbi.nlm.nih.gov/pubmed/27503008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13064-016-0069-7
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires