Prevention of mother-to-child transmission of hepatitis B virus: a phase III, placebo-controlled, double-blind, randomized clinical trial to assess the efficacy and safety of a short course of tenofovir disoproxil fumarate in women with hepatitis B virus e-antigen

BACKGROUND: Chronic hepatitis B virus (HBV) infection is complicated by cirrhosis and liver cancer. In Thailand, 6-7 % of adults are chronically infected with HBV. The risk of mother-to-child transmission (MTCT) of HBV has been estimated to be about 12 % when mothers have a high hepatitis B viral lo...

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Veröffentlicht in:BMC Infect Dis
Hauptverfasser: Jourdain, Gonzague, Ngo-Giang-Huong, Nicole, Cressey, Tim R., Hua, Lei, Harrison, Linda, Tierney, Camlin, Salvadori, Nicolas, Decker, Luc, Traisathit, Patrinee, Sirirungsi, Wasna, Khamduang, Woottichai, Bowonwatanuwong, Chureeratana, Puthanakit, Thanyawee, Siberry, George K., Watts, Diane Heather, Murphy, Trudy V., Achalapong, Jullapong, Hongsiriwon, Suchat, Klinbuayaem, Virat, Thongsawat, Satawat, Chung, Raymond T., Pol, Stanislas, Chotivanich, Nantasak
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2016
Schlagworte:
Study Protocol
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4977630/
https://ncbi.nlm.nih.gov/pubmed/27506549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12879-016-1734-5
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