Superoxide overproduction and kidney fibrosis: a new animal model

OBJECTIVE: To establish whether the mutation in the Immp2L gene induces renal fibrosis and whether aging exacerbates renal morphology in mice. METHODS: Female mutant mice with mutation in the inner mitochondrial membrane peptidase 2-like protein at 3 and 18 months of age were used. Renal fibrosis wa...

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Bibliografische gegevens
Gepubliceerd in:Einstein (Sao Paulo)
Hoofdauteurs: Guimarães-Souza, Nadia Karina, Yamaleyeva, Liliya Marsovna, Lu, Baisong, Ramos, Ana Claudia Mallet de Souza, Bishop, Colin Edward, Andersson, Karl Erik
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Instituto de Ensino e Pesquisa Albert Einstein 2015
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4977594/
https://ncbi.nlm.nih.gov/pubmed/25993073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/S1679-45082015AO3179
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