Superoxide overproduction and kidney fibrosis: a new animal model

OBJECTIVE: To establish whether the mutation in the Immp2L gene induces renal fibrosis and whether aging exacerbates renal morphology in mice. METHODS: Female mutant mice with mutation in the inner mitochondrial membrane peptidase 2-like protein at 3 and 18 months of age were used. Renal fibrosis wa...

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Enregistré dans:
Détails bibliographiques
Publié dans:Einstein (Sao Paulo)
Auteurs principaux: Guimarães-Souza, Nadia Karina, Yamaleyeva, Liliya Marsovna, Lu, Baisong, Ramos, Ana Claudia Mallet de Souza, Bishop, Colin Edward, Andersson, Karl Erik
Format: Artigo
Langue:Inglês
Publié: Instituto de Ensino e Pesquisa Albert Einstein 2015
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4977594/
https://ncbi.nlm.nih.gov/pubmed/25993073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1590/S1679-45082015AO3179
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