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Pro-arrhythmogenic effects of CACNA1C G1911R mutation in human ventricular tachycardia: insights from cardiac multi-scale models

Mutations in the CACNA1C gene are associated with ventricular tachycardia (VT). Although the CACNA1C mutations were well identified in patients with cardiac arrhythmias, mechanisms by which cardiac arrhythmias are generated in such genetic mutation conditions remain unclear. In this study, we identi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Bai, Jieyun, Wang, Kuanquan, Li, Qince, Yuan, Yongfeng, Zhang, Henggui
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4977499/
https://ncbi.nlm.nih.gov/pubmed/27502440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31262
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