Nitric oxide circulates in mammalian plasma primarily as an S-nitroso adduct of serum albumin.

We have recently shown that nitric oxide or authentic endothelium-derived relaxing factor generated in a biologic system reacts in the presence of specific protein thiols to form S-nitrosoprotein derivatives that have endothelium-derived relaxing factor-like properties. The single free cysteine of s...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Stamler, J S, Jaraki, O, Osborne, J, Simon, D I, Keaney, J, Vita, J, Singel, D, Valeri, C R, Loscalzo, J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1992
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49773/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1502182/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.16.7674
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