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The effect of sex and irritable bowel syndrome on HPA axis response and peripheral glucocorticoid receptor expression

BACKGROUND AND AIMS: Dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis has been reported in irritable bowel syndrome (IBS). Enhanced HPA axis response has been associated with reduced glucocorticoid receptor (GR) mediated negative feedback inhibition. We aimed to study the effects of IB...

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Publicado en:Psychoneuroendocrinology
Autores principales: Videlock, Elizabeth J., Shih, Wendy, Adeyemo, Mopelola, Mahurkar-Joshi, Swapna, Presson, Angela P., Polytarchou, Christos, Alberto, Melissa, Iliopoulos, Dimitrios, Mayer, Emeran A., Chang, Lin
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4977028/
https://ncbi.nlm.nih.gov/pubmed/27038676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.psyneuen.2016.03.016
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