Combined GSTM1-Null, GSTT1-Active, GSTA1 Low-Activity and GSTP1-Variant Genotype Is Associated with Increased Risk of Clear Cell Renal Cell Carcinoma

The aim of this study was to evaluate specific glutathione S-transferase (GST) gene variants as determinants of risk in patients with clear cell renal cell carcinoma (cRCC), independently or simultaneously with established RCC risk factors, as well as to discern whether phenotype changes reflect gen...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Coric, Vesna M., Simic, Tatjana P., Pekmezovic, Tatjana D., Basta-Jovanovic, Gordana M., Savic Radojevic, Ana R., Radojevic-Skodric, Sanja M., Matic, Marija G., Dragicevic, Dejan P., Radic, Tanja M., Bogdanovic, Ljiljana M., Dzamic, Zoran M., Pljesa-Ercegovac, Marija S.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976979/
https://ncbi.nlm.nih.gov/pubmed/27500405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160570
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