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Distinct molecular pathways mediate glial activation and engulfment of axonal debris after axotomy

Glial cells efficiently recognize and clear cellular debris after nervous system injury to maintain brain homeostasis, but pathways governing glial responses to neural injury remain poorly defined. We identify the Drosophila guanine-nucleotide exchange factor (GEF) complex Crk/Mbc/dCed-12, and the s...

詳細記述

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書誌詳細
出版年:Nat Neurosci
主要な著者: Ziegenfuss, Jennifer S., Doherty, Johnna, Freeman, Marc R.
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976689/
https://ncbi.nlm.nih.gov/pubmed/22706267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3135
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