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Distinct molecular pathways mediate glial activation and engulfment of axonal debris after axotomy
Glial cells efficiently recognize and clear cellular debris after nervous system injury to maintain brain homeostasis, but pathways governing glial responses to neural injury remain poorly defined. We identify the Drosophila guanine-nucleotide exchange factor (GEF) complex Crk/Mbc/dCed-12, and the s...
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Pubblicato in: | Nat Neurosci |
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Autori principali: | , , |
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
2012
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4976689/ https://ncbi.nlm.nih.gov/pubmed/22706267 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn.3135 |
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