Fibroblast growth factor 21 deficiency exacerbates chronic alcohol-induced hepatic steatosis and injury

Fibroblast growth factor 21 (FGF21) is a hepatokine that regulates glucose and lipid metabolism in the liver. We sought to determine the role of FGF21 in hepatic steatosis in mice exposed to chronic alcohol treatment and to discern underlying mechanisms. Male FGF21 knockout (FGF21 KO) and control (W...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Liu, Yanlong, Zhao, Cuiqing, Xiao, Jian, Liu, Liming, Zhang, Min, Wang, Cuiling, Wu, Guicheng, Zheng, Ming-Hua, Xu, Lan-Man, Chen, Yong-Ping, Mohammadi, Moosa, Chen, Shao-Yu, Cave, Matthew, McClain, Craig, Li, Xiaokun, Feng, Wenke
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2016
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976373/
https://ncbi.nlm.nih.gov/pubmed/27498701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31026
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