A new animal model containing human SCARB2 and lacking stat-1 is highly susceptible to EV71

Enterovirus 71 (EV71) is a major threat to children worldwide. Children infected with EV71 could develop subclinical infection and hand-foot-and -mouth disease (HFMD). In severe cases, patients could develop encephalitis, paralysis, pulmonary edema, and death. A more user-friendly and robust animal...

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Udgivet i:Sci Rep
Main Authors: Liou, An-Ting, Wu, Szu-Yao, Liao, Chun-Che, Chang, Ya-Shu, Chang, Chih-Shin, Shih, Chiaho
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976353/
https://ncbi.nlm.nih.gov/pubmed/27499235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31151
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