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Endocrine disrupting chemical, bisphenol-A, induces breast cancer associated gene HOXB9 expression in vitro and in vivo

HOXB9 is a homeobox-containing gene that plays a key role in mammary gland development and is associated with breast and other types of cancer. Here, we demonstrate that HOXB9 expression is transcriptionally regulated by estradiol (E2), in vitro and in vivo. We also demonstrate that the endocrine di...

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Detalhes bibliográficos
Publicado no:Gene
Main Authors: Deb, Paromita, Bhan, Arunoday, Hussain, Imran, Ansari, Khairul I., Bobzean, Samara A., Pandita, Tej K, Perrotti, Linda I, Mandal, Subhrangsu S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4975976/
https://ncbi.nlm.nih.gov/pubmed/27182052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gene.2016.05.009
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